What is tardive
dyskinesia (TD)?

Tongue darting

Blinking

Dancing fingers

Not an actual patient
Uncontrollable movements of TD

TD means having movements you can’t control

Where are TD movements seen?

While it can occur anywhere in the body, TD is often seen in the

  • Lips
  • Jaw
  • Tongue
  • Eyes

TD can also affect the

  • Upper body
  • Arms/hands
  • Torso
  • Legs/feet

TD can result from taking certain medications, such as antipsychotics, for a long time.

What medications can cause TD?

You may have been prescribed an antipsychotic medication to treat conditions such as:

  • Depression

  • Bipolar disorder

  • Schizophrenia

TD can result from the use of other medications that treat upset stomach, nausea, and vomiting.

bottle-icon

Stopping or switching your antipsychotic medication may not be an effective way to manage TD.

Have you experienced any of the following movements in your body?

Not actual patients
Living with TD

TD affects everyone differently

If you suspect you have TD, your psychiatrist will perform several examinations. The most common areas of the body where they will look for TD symptoms are your face, torso, arms, and legs.

The first area that your psychiatrist may examine is your face, as it’s the most common and noticeable area where symptoms may occur. Some TD symptoms, especially in your feet and toes, are sometimes overlooked.

You can help your psychiatrist with the examination by writing down all the TD symptoms you’re experiencing beforehand and sharing the list.

notes-icon

The impact of TD goes beyond physical abilitya

Based on a survey, people reported TD can impact them emotionally or socially.

emotional-impact

Emotional Impact

TD can change the way people think and feel about themselves. Many people with TD reported feelings of anxiety, frustration, and low self-esteem. They also feel like a burden to loved ones.

social-impact

Social Impact

People with the uncontrollable movements of TD often feel self-conscious in social settings. This may affect their ability to do things in public, participate in social events, and maintain relationships with others.

aResults based on a survey of 267 people diagnosed with TD (n=74) or suspected of TD (n=193) who were asked, “Tardive dyskinesia may impact you in many different ways. To what extent has tardive dyskinesia impacted you in each of the following areas?” Answers ranged on a scale of 1 (not impacted at all) to 7 (extremely impacted).

Is TD impacting your life emotionally or socially? Talk to your psychiatrist and be open about how you’re feeling and how these feelings are affecting your personal life and relationships.

“The thing that was the most difficult was my upper body movements and my leg kicking even disturbed my husband to where neither of us could fall asleep in the same bed. That was really hard for me.”

—Allison, living with bipolar disorder and TD

How INGREZZA treats TD

The cause of TD and how INGREZZA® (valbenazine) capsules works

TD is associated with taking antipsychotic medications for 3 months or longer.

How does tardive dyskinesia work?

These medications may create abnormal dopamine signaling in the brain, which results in uncontrollable movements

How does tardive dyskinesia work?

INGREZZA is believed to reduce abnormal dopamine signaling, thereby reducing uncontrollable movements

Important Information

Approved Use

INGREZZA® (valbenazine) capsules is a prescription medicine used to treat adults with movements in the face, tongue, or other body parts that cannot be controlled (tardive dyskinesia).

It is not known if INGREZZA is safe and effective in children.

IMPORTANT SAFETY INFORMATION

Do not take INGREZZA if you:

  • are allergic to valbenazine, or any of the ingredients in INGREZZA.

INGREZZA may cause serious side effects, including:

  • Sleepiness (somnolence). Do not drive, operate heavy machinery, or do other dangerous activities until you know how INGREZZA affects you.
  • Heart rhythm problems (QT prolongation). INGREZZA may cause a heart problem known as QT prolongation.
  • Symptoms of QT prolongation may include: fast, slow, or irregular heartbeat, shortness of breath, dizziness or fainting.
  • Parkinson-like symptoms. Symptoms include: shaking, body stiffness, trouble moving or walking, or keeping your balance.

Tell your healthcare provider right away if you have a change in your heartbeat (a fast or irregular heartbeat), or if you faint.

Before taking INGREZZA, tell your healthcare provider about all of your medical conditions including if you: have liver or heart problems, are pregnant or plan to become pregnant, or are breastfeeding or plan to breastfeed.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements.

The most common side effect of INGREZZA is sleepiness (somnolence). Other side effects include changes in balance (balance problems, dizziness) or an increased risk of falls, headache, feelings of restlessness, dry mouth, constipation, and blurred vision.

These are not all of the possible side effects of INGREZZA. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Please see INGREZZA full Product Information

IMPORTANT SAFETY INFORMATION PRODUCT INFORMATION