Frequently asked questions about INGREZZA

INGREZZA is a once-daily FDA-approved treatment for adults with uncontrollable movements of TD.

It is not known if INGREZZA is safe and effective in children.

Do not take INGREZZA if you are allergic to valbenazine or any of the ingredients in INGREZZA.

Learn more about INGREZZA

Current research suggests that INGREZZA helps by correcting abnormal dopamine signaling; however, how INGREZZA works to treat TD is not fully understood.

• Dopamine is a chemical in the brain that helps control movement
• TD may be caused by too much dopamine signaling in the brain
• INGREZZA is believed to reduce extra dopamine signaling

Learn more about INGREZZA

INGREZZA is approved to treat TD in adults. Adults with mild, moderate, and severe uncontrollable movements of TD should talk to their healthcare provider about INGREZZA.

Learn more about INGREZZA

Many people taking INGREZZA 80 mg in a clinical study started to see improvements in as little as 2 weeks,^* and 7 out of 10 people had reduced movements at 6 weeks.^†

*INGREZZA was studied in a 6-week clinical trial. A total of 234 people participated in the study. Results were based on 79 people taking the recommended dose of 80 mg.

^†Patients had at least a 1-point reduction on an uncontrollable movement severity scale at 6 weeks vs before treatment. This post-clinical study evaluation included 70 patients taking INGREZZA 80 mg, measuring uncontrollable movements before starting treatment and at 6 weeks of treatment.

Learn more about INGREZZA

In a clinical study, psychiatric status remained stable overall in people taking INGREZZA for TD, including those who were also taking medicine for:

• Depression
• Bipolar disorder
• Schizophrenia/schizoaffective disorder
• Anxiety disorder

People taking INGREZZA for TD can stay on their current dose of most mental health medicines.

Learn about taking INGREZZA

In a clinical study, 7 out of 10 people taking INGREZZA 80 mg saw reduction in uncontrollable body movements at 6 weeks.^* And in the same clinical study, many people taking INGREZZA began to see results in as little as 2 weeks.^† During a long-term study, INGREZZA provided continued reduction in uncontrollable body movements through 48 weeks.

*Patients had at least a 1-point reduction on an uncontrollable movement severity scale at 6 weeks vs before treatment. This post-clinical study evaluation included 70 patients taking INGREZZA 80 mg, measuring uncontrollable movements before starting treatment and at 6 weeks of treatment.

^†INGREZZA was studied in a 6-week clinical trial. A total of 234 people participated in the study. Results were based on 79 people taking the recommended dose of 80 mg.

Learn more about INGREZZA

Ask your healthcare provider to explain how INGREZZA works, when to expect results, and to clarify the goals of your treatment, including what you should look for to know if it’s working.

Learn more about INGREZZA

In a clinical study, the most common side effect of INGREZZA in people with tardive dyskinesia was sleepiness.

Other serious side effects were heart rhythm problems and abnormal movements, including shaking, body stiffness, trouble moving or walking, or keeping your balance. Tell your healthcare provider right away if you have a change in your heartbeat (a fast or irregular heartbeat), or if you faint.

Other side effects include:

• Changes in balance (balance problems, dizziness) or increased risk of falls
• Headache
• Feelings of restlessness
• Dry mouth
• Constipation
• Blurred vision

These are not all of the possible side effects of INGREZZA. Call your healthcare provider for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit MedWatch at www.fda.gov/medwatch or call 1-800-FDA-1088..

Taking INGREZZA is simple:

• Always one capsule, once a day
• Taken any time
• With or without food

People taking INGREZZA for TD can stay on their current dose of most mental health medicines.

Your healthcare provider will tell you how much INGREZZA to take and when to take it. Do not stop taking INGREZZA without talking to your healthcare provider first.

If you take too much INGREZZA, call your poison control center at 1-800-222-1222.

Learn about taking INGREZZA

INGREZZA is a single capsule that is taken once a day with or without food.

Your healthcare provider will tell you how much INGREZZA to take and when to take it. Do not stop taking INGREZZA without talking to your healthcare provider first.

If you take too much INGREZZA, call your poison control center at 1-800-222-1222.

Learn about taking INGREZZA

Yes. The INBRACE® Support Program could help you save on your INGREZZA prescription.

You may pay as little as a $0 copay on your INGREZZA prescription with the INGREZZA Savings Program. If you are eligible, a Savings Card may be applied automatically, which may help you save money on your INGREZZA prescription.*

*This offer is valid only for patients who have commercial (nongovernment-funded) insurance. Additional terms and conditions apply.

Learn more about the INBRACE^® Support Program

Call or email your healthcare provider (if it’s an option) and ask them to repeat any information you didn’t understand at your appointment or to explain it differently—they may not realize they might be using confusing, scientific terms.

Also, consider including a family member, care partner, or friend to join you at your next appointment. They can help you better understand and remember your healthcare provider’s advice and instructions.

There’s an entire community of support. Below are organizations that can help.

Whether your uncontrollable body movements are mild, moderate, or severe, connecting with a psychiatry or neurology healthcare provider who may be able to help you diagnose and treat tardive dyskinesia (TD) is important.

Find a specialist

When your prescription is authorized, you’ll receive calls from the specialty pharmacy to verify your important information. The pharmacy will call to verify your information each time your prescription needs to be refilled.

(Note: These calls may come from an unidentified toll-free number, so it’s important to answer your phone.)

If your healthcare provider sent your prescription to a specialty pharmacy, INGREZZA will be shipped directly to you via overnight mail. A specialty pharmacy provides medicines that aren’t typically available at your local retail pharmacy. In some cases, your healthcare provider may send your prescription to a local select pharmacy. INGREZZA is distributed through select specialty and local affiliated pharmacies.

Yes—resources are available to help you start and stay on track with treatment.

Find treatment resources

Are you taking INGREZZA to treat tardive dyskinesia (TD)? Do you have an interest in sharing your story? If you’re a US resident and 18 years or older, please call 1-844-814-5376 to find out if you are eligible to participate in our Patient Ambassador Program. Any information you provide will be kept in accordance with our privacy policy.

Please note that not all candidates will be selected to participate in the program.