What is tardive
dyskinesia (TD)?

Tongue darting

Blinking

Dancing fingers

Not an actual patient

TD means having movements you can’t control

What are signs and symptoms of TD?

While it can occur anywhere in the body, TD signs and symptoms are often seen in the:

  • Lips
  • Jaw
  • Tongue
  • Eyes

TD can also affect the:

  • Upper body
  • Arms/hands
  • Torso
  • Legs/feet

TD can result from taking certain mental health medicines for a while.

Have you experienced any of the following movements in your body?

Not actual patients

What medications can cause TD?

You may have been prescribed an antipsychotic medication to treat conditions such as:

  • Depression

  • Bipolar disorder

  • Schizophrenia

TD can result from the use of these and other medications that treat upset stomach, nausea, and vomiting.

bottle-icon

If you are currently taking antipsychotic medication, do not stop, adjust, or switch your medication without talking to your doctor. Continue taking your medication as prescribed and be sure to talk to your doctor about TD and FDA-approved treatments, like INGREZZA® (valbenazine) capsules.

TD affects everyone differently

If you suspect you have TD, your doctor will perform several examinations. Common areas of the body where they will look for TD symptoms are your face, torso, arms, and legs. TD symptoms, especially in your feet and toes, are sometimes overlooked.

The impact of TD goes beyond physical abilitya

Based on a survey, people reported TD can impact them emotionally or socially.

emotional-impact

Emotional Impact

TD can change the way people think and feel about themselves. Many people with TD reported feelings of anxiety, frustration, and low self-esteem. They also feel like a burden to loved ones.

social-impact

Social Impact

People with the uncontrollable movements of TD reported feeling self-conscious in social settings. This may affect their ability to do things in public, participate in social events, and maintain relationships with others.

aResults based on a survey of 267 people diagnosed with TD (n=74) or suspected of TD (n=193) who were asked, “Tardive dyskinesia may impact you in many different ways. To what extent has tardive dyskinesia impacted you in each of the following areas?” Answers ranged on a scale of 1 (not impacted at all) to 7 (extremely impacted).

Is TD impacting your life emotionally or socially? Talk to your psychiatrist and be open about how you’re feeling and how these feelings are affecting your personal life and relationships.

Caring for someone with TD

If you’re the care partner of someone with uncontrollable body movements from TD, it’s helpful to remember that your loved one:

  • May not know if their uncontrollable movements are TD
  • Might not want to seek help because they don't understand what's happening with their body

Helpful tip: Record your loved one’s uncontrollable body movements so they can share them with their doctor during an in-office or telehealth appointment.

Start a discussion—encourage your loved one to talk to their doctor about TD, and if possible, join them for the appointment. You may be able to help them better understand and remember their doctor's advice and instructions.

Speech bubbles.

“[Because of my uncontrollable body movements] I was extremely self-conscious, embarrassed, and withdrawn. I had a very active lifestyle before these movements.”

—Moira, history of bipolar disorder and depression

Moira was compensated by Neurocrine Biosciences, Inc. to share her story

Tips for your next appointment

Discussion guide icon.

Bring these resourcesour Doctor Discussion Guide to your next appointment to help you and your doctor have a better conversation about TD and INGREZZA.

Doctor discussion guide.

Doctor Discussion Guide

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Patient brochure.

Patient brochure

Indication and Important Safety Information

Do not take INGREZZA if you are allergic to valbenazine, or any of the ingredients in INGREZZA.

Important Information

Approved Use

INGREZZA® (valbenazine) capsules is a prescription medicine used to treat adults with movements in the face, tongue, or other body parts that cannot be controlled (tardive dyskinesia).

It is not known if INGREZZA is safe and effective in children.

IMPORTANT SAFETY INFORMATION

Do not take INGREZZA if you:

  • are allergic to valbenazine, or any of the ingredients in INGREZZA.

INGREZZA may cause serious side effects, including:

  • Sleepiness (somnolence). Do not drive, operate heavy machinery, or do other dangerous activities until you know how INGREZZA affects you.
  • Heart rhythm problems (QT prolongation). INGREZZA may cause a heart problem known as QT prolongation.
  • Symptoms of QT prolongation may include:
    • fast, slow, or irregular heartbeat
    • shortness of breath
    • dizziness or fainting
  • Tell your healthcare provider right away if you have a change in your heartbeat (a fast or irregular heartbeat), or if you faint.
  • Parkinson-like symptoms. Symptoms include: shaking, body stiffness, trouble moving or walking, or keeping your balance.

Before taking INGREZZA, tell your healthcare provider about all of your medical conditions including if you: have liver or heart problems, are pregnant or plan to become pregnant, or are breastfeeding or plan to breastfeed.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements.

The most common side effect of INGREZZA is sleepiness (somnolence). Other side effects include changes in balance (balance problems, dizziness) or an increased risk of falls, headache, feelings of restlessness, dry mouth, constipation, and blurred vision.

These are not all of the possible side effects of INGREZZA. Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit MedWatch at www.fda.gov/medwatch or call 1-800-FDA-1088.

Please see accompanying INGREZZA full Product Information

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