Treating tardive dyskinesia (TD) and results with INGREZZA

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Treating tardive dyskinesia (TD) and results with INGREZZA

Some mental health medicines (antipsychotics) can cause abnormal dopamine signaling in the brain, which can lead to uncontrollable body movements from tardive dyskinesia that are unlikely to improve without treatment.

INGREZZA® (valbenazine) capsules is thought to reduce extra dopamine signaling while working directly in the region of the brain that causes uncontrollable movements of tardive dyskinesia (TD). How INGREZZA works to treat TD is not fully understood.

  • Dopamine is a chemical in the brain that helps control movement
  • TD may be caused by too much dopamine signaling in the brain
  • INGREZZA is believed to reduce extra dopamine signaling

INGREZZA is proven to reduce uncontrollable body movements—and it's the only once-daily treatment for TD.

Clinical study results

In a clinical study, 7 out of 10 people taking INGREZZA 80 mg saw reduction in uncontrollable body movements at 6 weeks.

And in the same clinical study, many people taking INGREZZA began to see results in as little as 2 weeks.*

*INGREZZA was studied in a 6-week clinical trial. A total of 234 people participated in the study. Results were based on 79 people taking the recommended dose of 80 mg.

In a long-term study, INGREZZA provided continued reduction in uncontrollable body movements through 48 weeks.

*INGREZZA was studied in a 6-week clinical trial. A total of 234 people participated in the study. Results were based on 79 people taking the recommended dose of 80 mg.

  • Patients had at least a 1-point reduction on an uncontrollable movement severity scale at 6 weeks vs before treatment.
  • This post-clinical study evaluation included 70 patients taking INGREZZA 80 mg, measuring uncontrollable movements before starting treatment and at 6 weeks of treatment.

Learn more about the INGREZZA clinical study

For questions about INGREZZA, call 1‑84‑INGREZZA (1‑844‑647‑3992)

Did you know?

Treatment is usually necessary to reduce uncontrollable body movements from TD. INGREZZA is the only once-daily treatment for TD.

INGREZZA side effects

In a clinical study, the most common side effect while taking INGREZZA was sleepiness.

INGREZZA may cause serious side effects, including:

  • Sleepiness
  • Heart rhythm problems
  • Abnormal movements, including shaking, body stiffness, trouble moving or walking, or keeping your balance

Other side effects include:

  • Changes in balance (balance problems, dizziness) or increased risk of falls
  • Headache
  • Feelings of restlessness
  • Dry mouth
  • Constipation
  • Blurred vision

These are not all of the possible side effects of INGREZZA.

If you experience side effects, call your healthcare provider for medical advice. To report side effects to the FDA, call 1-800-FDA-1088.

Doctor Discussion Guide

Looking for help talking to your healthcare provider about your TD movements? View our discussion guide.

You can use our discussion guide to have a more productive conversation with your healthcare provider about tardive dyskinesia (TD) and INGREZZA. Ask your healthcare provider about staying on your current dose of most mental health medicines while treating your TD.

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Ready to start a conversation about TD treatment? Find a specialist.

Whether your uncontrollable body movements are mild, moderate, or severe, connecting with a psychiatry or neurology healthcare provider who has experience diagnosing and treating TD is important.

Enter your ZIP code to find a specialist near you and ask about reducing TD movements with INGREZZA—the only once‑daily treatment for TD.a

  • Neurocrine Biosciences, Inc. is providing this service to help patients find healthcare professionals in their area who have experience with tardive dyskinesia (TD).

No fees have been received by or paid to healthcare professionals for inclusion in this locator directory. Inclusion of a healthcare professional in this directory does not represent an endorsement by or a recommendation from Neurocrine Biosciences, nor does it imply that the healthcare professional on the list will determine that a Neurocrine Biosciences product is right for you. Neurocrine Biosciences makes no warranty as to the credentials, skill, or outcomes of the listed professional.

Information posted to this site is provided for educational and informational purposes only. You are ultimately responsible for the selection of a healthcare professional and it is an important decision that you should consider carefully. This healthcare professional locator tool is just one source of information available to you.

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