Frequently Asked Questions

Frequently asked questions about INGREZZA® (valbenazine) capsules

  • 1. 

    What is INGREZZA?

    INGREZZA is a medicine that was designed to treat tardive dyskinesia (TD).

    It is the #1 most prescribed treatment for TD and is used to treat adults with movements in the face, tongue, or other body parts that cannot be controlled. It is not known if INGREZZA is safe and effective in children.

    Do not take INGREZZA if you are allergic to valbenazine or any of the ingredients in INGREZZA.

    INGREZZA is taken once a day in capsule form and is available in 2 different doses.

  • 2. 

    How does INGREZZA work?

    Though how it works isn't fully understood, INGREZZA is thought to reduce dopamine signaling in the brain—while working directly in the region of the brain that causes the uncontrollable movements of TD.

    • INGREZZA is believed to reduce extra dopamine signaling
    • Dopamine is a chemical in the brain that helps control movement
    • TD may be caused by too much dopamine signaling in the brain
  • 3. 

    Does INGREZZA improve uncontrollable movements?

    Yes—about 70% of patients taking INGREZZA 80 mg saw reduction in TD movements at 6 weeks.*

    • This post-clinical study evaluation included 70 patients taking INGREZZA 80 mg, measuring uncontrollable movements before starting treatment and at 6 weeks of treatment.

    *Patients had at least a 1-point reduction on an uncontrollable movement severity scale at 6 weeks vs before treatment.

  • 4. 

    Will I keep seeing positive results with INGREZZA?

    In a clinical study, people on INGREZZA saw early improvements in TD (at 6 weeks) and continued to see reduction in uncontrollable body movements through 48 weeks.

  • 5. 

    How do I know INGREZZA is working?

    Ask your doctor to explain how INGREZZA works, when to expect results, and to clarify the goals of your treatment, including what you should look for to know if it's working.

  • 6. 

    What are common side effects of INGREZZA?

    In clinical studies, the most common side effect was sleepiness.

    Other serious side effects were heart rhythm problems and abnormal movements, including shaking, body stiffness, trouble moving or walking, or keeping your balance. Tell your doctor right away if you have a change in your heartbeat (a fast or irregular heartbeat), or if you faint.

    Other side effects included:

    • Changes in balance (balance problems, dizziness) or increased risk of falls
    • Headache
    • Feelings of restlessness
    • Dry mouth
    • Constipation
    • Blurred vision

    These are not all of the possible side effects of INGREZZA. Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit MedWatch at www.fda.gov/medwatch or call 1-800-FDA-1088.

  • 7. 

    Does INGREZZA have dosing options?

    Yes, once daily INGREZZA has 40 mg and 80 mg doses.

    Your doctor will start you on a 40 mg dose of INGREZZA. After 1 week, they may increase your dose to 80 mg.

    Your doctor may also keep you on 40 mg depending on your treatment needs.

  • 8. 

    How should I take INGREZZA?

    INGREZZA is a capsule that is taken once a day with or without food. Take INGREZZA exactly as your doctor tells you.

    Your healthcare provider will tell you how much INGREZZA to take and when to take it. Do not stop taking INGREZZA without talking to your doctor first.

    If you take too much INGREZZA, call your poison control center at 1-800-222-1222.

  • 9. 

    Are there savings programs available for INGREZZA?

    Ask your doctor to enroll you in the INBRACE® Support Program.

    The pharmacy will verify your insurance coverage and work with your healthcare provider to complete any additional paperwork required by your insurance.

    The INBRACE® Support Program can help by providing information about options to help pay for INGREZZA.

    You may be eligible for a $0 copay on your INGREZZA prescription.*

    *This offer is valid only if you have commercial (nongovernment-funded) insurance. Additional terms and conditions apply.

  • 10. 

    I didn't understand what my doctor said to me. What can I do?

    Call or email your doctor (if it's an option) and ask them to repeat any information you didn't understand at your appointment or to explain it differently—they may not realize they might be using confusing, scientific terms.

    Also, consider including a family member, care partner, or friend to join you at your next appointment. They can help you better understand and remember your doctor's advice and instructions.

  • 11. 

    What organizations might be helpful?

    There's a community to help support you.

    Below are organizations that can help if you have TD or care for someone with TD.

Indication and Important Safety Information

Do not take INGREZZA if you are allergic to valbenazine, or any of the ingredients in INGREZZA.

Important Information

Approved Use

INGREZZA® (valbenazine) capsules is a prescription medicine used to treat adults with movements in the face, tongue, or other body parts that cannot be controlled (tardive dyskinesia).

It is not known if INGREZZA is safe and effective in children.

IMPORTANT SAFETY INFORMATION

Do not take INGREZZA if you:

  • are allergic to valbenazine, or any of the ingredients in INGREZZA.

INGREZZA may cause serious side effects, including:

  • Sleepiness (somnolence). Do not drive, operate heavy machinery, or do other dangerous activities until you know how INGREZZA affects you.
  • Heart rhythm problems (QT prolongation). INGREZZA may cause a heart problem known as QT prolongation.
  • Symptoms of QT prolongation may include:
    • fast, slow, or irregular heartbeat
    • shortness of breath
    • dizziness or fainting
  • Tell your healthcare provider right away if you have a change in your heartbeat (a fast or irregular heartbeat), or if you faint.
  • Parkinson-like symptoms. Symptoms include: shaking, body stiffness, trouble moving or walking, or keeping your balance.

Before taking INGREZZA, tell your healthcare provider about all of your medical conditions including if you: have liver or heart problems, are pregnant or plan to become pregnant, or are breastfeeding or plan to breastfeed.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements.

The most common side effect of INGREZZA is sleepiness (somnolence). Other side effects include changes in balance (balance problems, dizziness) or an increased risk of falls, headache, feelings of restlessness, dry mouth, constipation, and blurred vision.

These are not all of the possible side effects of INGREZZA. Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit MedWatch at www.fda.gov/medwatch or call 1-800-FDA-1088.

Please see accompanying INGREZZA full Product Information

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